c-Jun N-terminal kinase mediated VEGFR2 sustained phosphorylation is critical for VEGFA-induced angiogenesis in vitro and in vivo. [electronic resource]
- Cell biochemistry and biophysics Sep 2012
- 17-27 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1559-0283
10.1007/s12013-012-9363-0 doi
Animals Anthracenes--pharmacology Cell Movement Cell Survival Cells, Cultured Dose-Response Relationship, Drug Enzyme Activation Human Umbilical Vein Endothelial Cells--cytology Humans Indoles--pharmacology JNK Mitogen-Activated Protein Kinases--metabolism MAP Kinase Signaling System Mice Mice, Inbred C57BL Neovascularization, Physiologic Phosphorylation Pyrroles--pharmacology RNA, Small Interfering--metabolism Recombinant Proteins--pharmacology Transfection Vascular Endothelial Growth Factor A--pharmacology Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors