TY - GEN AU - Miyoshi,Seigo AU - Hamada,Hironobu AU - Hamaguchi,Naohiko AU - Kato,Aki AU - Katayama,Hitoshi AU - Irifune,Kazunori AU - Ito,Ryoji AU - Miyazaki,Tatsuhiko AU - Okura,Takafumi AU - Higaki,Jitsuo TI - Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo SN - 1791-2423 PY - 2012///1019 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - drug effects KW - Butadienes KW - Cell Proliferation KW - Chromones KW - Drug Synergism KW - G1 Phase Cell Cycle Checkpoints KW - Humans KW - MAP Kinase Kinase Kinases KW - antagonists & inhibitors KW - MAP Kinase Signaling System KW - Male KW - Mesothelioma KW - drug therapy KW - Mice KW - Mice, SCID KW - Morpholines KW - Nitriles KW - Phosphatidylinositol 3-Kinases KW - metabolism KW - Phosphoinositide-3 Kinase Inhibitors KW - Pleural Neoplasms KW - Tumor Burden KW - Tumor Cells, Cultured KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.3892/ijo.2012.1462 ER -