Michaelsen, Signe R

Single agent- and combination treatment with two targeted suicide gene therapy systems is effective in chemoresistant small cell lung cancer cells. [electronic resource] - The journal of gene medicine Jul 2012 - 445-58 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-2254

10.1002/jgm.2630 doi


Animals
Apoptosis
Cell Line, Tumor
Cell Survival
Chemotherapy, Adjuvant
Cytosine Deaminase--genetics
Drug Resistance, Neoplasm
Drug Therapy, Combination
Escherichia coli--enzymology
Flucytosine--therapeutic use
Genes, Transgenic, Suicide--genetics
Genetic Therapy--methods
Humans
Lung Neoplasms--therapy
Male
Mice
Nitroreductases--therapeutic use
Pentosyltransferases--genetics
Promoter Regions, Genetic--genetics
Repressor Proteins--genetics
Small Cell Lung Carcinoma--therapy
Yeasts--enzymology