GSI-I has a better effect in inhibiting hepatocellular carcinoma cell growth than GSI-IX, GSI-X, or GSI-XXI. [electronic resource]
- Anti-cancer drugs Aug 2012
- 683-90 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1473-5741
10.1097/CAD.0b013e3283549a22 doi
Amyloid Precursor Protein Secretases--antagonists & inhibitors Antineoplastic Agents--therapeutic use Basic Helix-Loop-Helix Transcription Factors--drug effects Benzodiazepinones--therapeutic use Calcium-Binding Proteins--drug effects Carbamates--therapeutic use Carcinoma, Hepatocellular--drug therapy Cell Line, Tumor Cell Proliferation--drug effects Cell Survival Dipeptides--therapeutic use Gene Expression Regulation, Neoplastic--drug effects Genes, myc--drug effects Hep G2 Cells Homeodomain Proteins--drug effects Humans Intercellular Signaling Peptides and Proteins--genetics Jagged-1 Protein Liver Neoplasms--drug therapy Membrane Proteins--drug effects Oligopeptides--therapeutic use Receptors, Notch--antagonists & inhibitors Serrate-Jagged Proteins Transcription Factor HES-1