TY - GEN AU - CastaƱo Betancourt,Martha C AU - Cailotto,Frederic AU - Kerkhof,Hanneke J AU - Cornelis,Frederique M F AU - Doherty,Sally A AU - Hart,Deborah J AU - Hofman,Albert AU - Luyten,Frank P AU - Maciewicz,Rose A AU - Mangino,Massimo AU - Metrustry,Sarah AU - Muir,Kenneth AU - Peters,Marjolein J AU - Rivadeneira,Fernando AU - Wheeler,Maggie AU - Zhang,Weiya AU - Arden,Nigel AU - Spector,Tim D AU - Uitterlinden,Andre G AU - Doherty,Michael AU - Lories,Rik J U AU - Valdes,Ana M AU - van Meurs,Joyce B J TI - Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis SN - 1091-6490 PY - 2012///0802 KW - Age Factors KW - Animals KW - Cartilage, Articular KW - pathology KW - Cell Line KW - Chondrocytes KW - cytology KW - Chondrogenesis KW - genetics KW - Genetic Variation KW - Genome-Wide Association Study KW - Hepatocyte Nuclear Factor 1-alpha KW - metabolism KW - Histone-Lysine N-Methyltransferase KW - Humans KW - Methyltransferases KW - Mice KW - Osteoarthritis, Hip KW - epidemiology KW - Risk Factors KW - Wnt Signaling Pathway KW - physiology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1119899109 ER -