Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America May 2012
- 8218-23 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1091-6490
10.1073/pnas.1119899109 doi
Age Factors Animals Cartilage, Articular--pathology Cell Line Chondrocytes--cytology Chondrogenesis--genetics Genetic Variation Genome-Wide Association Study Hepatocyte Nuclear Factor 1-alpha--metabolism Histone-Lysine N-Methyltransferase Humans Methyltransferases--genetics Mice Osteoarthritis, Hip--epidemiology Risk Factors Wnt Signaling Pathway--physiology