Securin enhances the anti-cancer effects of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075) in human colorectal cancer cells. [electronic resource]
- PloS one 2012
- e36006 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0036006 doi
Antineoplastic Agents--pharmacology Apoptosis--drug effects CDC2 Protein Kinase--metabolism Caspases--metabolism Colorectal Neoplasms--metabolism DNA Repair--drug effects G2 Phase Cell Cycle Checkpoints--drug effects HCT116 Cells Humans Indoles--pharmacology JNK Mitogen-Activated Protein Kinases--metabolism M Phase Cell Cycle Checkpoints--drug effects Neoplasm Proteins--genetics Phosphorylation--drug effects Securin p38 Mitogen-Activated Protein Kinases--metabolism