Tiaden, André N

Detrimental role for human high temperature requirement serine protease A1 (HTRA1) in the pathogenesis of intervertebral disc (IVD) degeneration. [electronic resource] - The Journal of biological chemistry Jun 2012 - 21335-45 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M112.341032 doi


Cell Line
Collagenases--biosynthesis
Extracellular Matrix--genetics
Female
Fibronectins--genetics
Gene Expression Regulation, Enzymologic
High-Temperature Requirement A Serine Peptidase 1
Humans
Intervertebral Disc--enzymology
Intervertebral Disc Degeneration--enzymology
MAP Kinase Kinase 1--genetics
Male
Polymorphism, Single Nucleotide
Proteolysis
Recombinant Proteins--biosynthesis
Serine Endopeptidases--biosynthesis