Wang, Fang <br/><br/>
Axitinib targeted cancer stemlike cells to enhance efficacy of chemotherapeutic drugs via inhibiting the drug transport function of ABCG2.  [electronic resource] 

 -  Molecular medicine (Cambridge, Mass.)  Jul 2012 
 - 887-98 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1528-3658 
<br/><br/><label>Standard No.: </label>10.2119/molmed.2011.00444  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily G, Member 2<br/>ATP-Binding Cassette Transporters--antagonists & inhibitors<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Axitinib<br/>Biological Transport--drug effects<br/>Cell Line, Tumor<br/>Drug Resistance, Neoplasm--genetics<br/>Female<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Imidazoles--pharmacology<br/>Indazoles--pharmacology<br/>Male<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Inbred NOD<br/>Mice, Nude<br/>Mice, SCID<br/>Mitogen-Activated Protein Kinase 1--metabolism<br/>Mitogen-Activated Protein Kinase 3--metabolism<br/>Neoplasm Proteins--antagonists & inhibitors<br/>Neoplasms--genetics<br/>Neoplastic Stem Cells--drug effects<br/>Phosphorylation--drug effects<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Xenograft Model Antitumor Assays