TY  - GEN
AU  - Krop,Ian
AU  - Demuth,Tim
AU  - Guthrie,Tina
AU  - Wen,Patrick Y
AU  - Mason,Warren P
AU  - Chinnaiyan,Prakash
AU  - Butowski,Nicholas
AU  - Groves,Morris D
AU  - Kesari,Santosh
AU  - Freedman,Steven J
AU  - Blackman,Samuel
AU  - Watters,James
AU  - Loboda,Andrey
AU  - Podtelezhnikov,Alexei
AU  - Lunceford,Jared
AU  - Chen,Cong
AU  - Giannotti,Maxine
AU  - Hing,Jeremy
AU  - Beckman,Robert
AU  - Lorusso,Patricia
TI  - Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors
SN  - 1527-7755
PY  - 2012///1112
KW  - Administration, Oral
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Amyloid Precursor Protein Secretases
KW  - antagonists & inhibitors
KW  - Benzene Derivatives
KW  - Cohort Studies
KW  - Dose-Response Relationship, Drug
KW  - Drug Administration Schedule
KW  - Female
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Neoplasms
KW  - drug therapy
KW  - Propionates
KW  - adverse effects
KW  - Sulfones
KW  - Treatment Outcome
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1200/JCO.2011.39.1540
ER  -