TY  - GEN
AU  - Zhu,Bo
AU  - Shrivastava,Ashutosh
AU  - Luongo,Cristina
AU  - Chen,Ting
AU  - Harney,John W
AU  - Marsili,Alessandro
AU  - Tran,Thuy-Van
AU  - Bhadouria,Anulika
AU  - Mopala,Radhika
AU  - Steen,Amanda I
AU  - Larsen,P Reed
AU  - Zavacki,Ann Marie
TI  - Catalysis leads to posttranslational inactivation of the type 1 deiodinase and alters its conformation
SN  - 1479-6805
PY  - 2012///0920
KW  - Biocatalysis
KW  - drug effects
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Activation
KW  - Fluorescence Resonance Energy Transfer
KW  - HEK293 Cells
KW  - Hep G2 Cells
KW  - Humans
KW  - Iodide Peroxidase
KW  - chemistry
KW  - Luciferases
KW  - genetics
KW  - Luminescent Proteins
KW  - Mutation
KW  - Propylthiouracil
KW  - pharmacology
KW  - Protein Conformation
KW  - Protein Multimerization
KW  - Protein Processing, Post-Translational
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Sonication
KW  - Substrate Specificity
KW  - Triiodothyronine
KW  - metabolism
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1530/JOE-11-0459
ER  -