Lacey, David L <br/><br/>
Bench to bedside: elucidation of the OPG-RANK-RANKL pathway and the development of denosumab.  [electronic resource] 

 -  Nature reviews. Drug discovery  May 2012 
 - 401-19 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review 
<br/><br/><label>ISSN: </label>1474-1784 
<br/><br/><label>Standard No.: </label>10.1038/nrd3705  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Monoclonal--pharmacology<br/>Antibodies, Monoclonal, Humanized<br/>Bone Resorption--physiopathology<br/>Bone and Bones--metabolism<br/>Denosumab<br/>Drug Design<br/>Humans<br/>Osteoclasts--physiology<br/>Osteoprotegerin--metabolism<br/>RANK Ligand--antagonists & inhibitors<br/>Receptor Activator of Nuclear Factor-kappa B--metabolism<br/>Signal Transduction