TY - GEN AU - Garcia-Gomez,Antonio AU - Ocio,Enrique M AU - Crusoe,Edvan AU - Santamaria,Carlos AU - Hernández-Campo,Pilar AU - Blanco,Juan F AU - Sanchez-Guijo,Fermin M AU - Hernández-Iglesias,Teresa AU - Briñón,Jesús G AU - Fisac-Herrero,Rosa M AU - Lee,Francis Y AU - Pandiella,Atanasio AU - San Miguel,Jesús F AU - Garayoa,Mercedes TI - Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects SN - 1932-6203 PY - 2012///0910 KW - Anabolic Agents KW - pharmacology KW - Animals KW - Bone Remodeling KW - drug effects KW - Bone Resorption KW - metabolism KW - CSK Tyrosine-Protein Kinase KW - Cathepsin K KW - Cell Differentiation KW - Cell Line KW - Cell Proliferation KW - Dasatinib KW - Female KW - Humans KW - Integrin alphaVbeta3 KW - Leukocytes, Mononuclear KW - cytology KW - Mesenchymal Stem Cells KW - Mice KW - NFATC Transcription Factors KW - Osteoclasts KW - Phosphorylation KW - Protein Kinase Inhibitors KW - Protein Serine-Threonine Kinases KW - Protein-Tyrosine Kinases KW - Proto-Oncogene Proteins c-kit KW - Pyrimidines KW - Receptor, Platelet-Derived Growth Factor beta KW - antagonists & inhibitors KW - Thiazoles KW - Wnt Signaling Pathway KW - src-Family Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0034914 ER -