Blackburn, J S

Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency. [electronic resource] - Leukemia Sep 2012 - 2069-78 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-5551

10.1038/leu.2012.116 doi


Animals
Animals, Genetically Modified
Apoptosis
Biomarkers, Tumor--genetics
Blotting, Western
Cell Line, Tumor
Cell Proliferation
Cell Transformation, Neoplastic
Gene Expression Profiling
Gene Expression Regulation, Leukemic
Humans
Mice
Oligonucleotide Array Sequence Analysis
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--metabolism
Proto-Oncogene Proteins c-myc--metabolism
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
Receptor, Notch1--physiology
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Thymocytes
Zebrafish--genetics