Staedler, Davide

Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cells. [electronic resource] - Journal of medicinal chemistry Jun 2012 - 4990-5002 p. digital

Publication Type: Journal Article

1520-4804

10.1021/jm300256z doi


Alkynes--chemical synthesis
Angiogenesis Inhibitors--chemical synthesis
Animals
Anticholesteremic Agents--chemical synthesis
Antineoplastic Agents--chemical synthesis
Atorvastatin
Brain--blood supply
Carbamates--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Cricetinae
Cyclohexanes--chemical synthesis
Drug Screening Assays, Antitumor
Drug Synergism
Endothelial Cells--cytology
Heptanoic Acids--pharmacology
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Intramolecular Transferases--antagonists & inhibitors
Microsomes, Liver--enzymology
Neovascularization, Pathologic--pathology
Pyrroles--pharmacology
Structure-Activity Relationship