TY - GEN AU - Dyavar Shetty,Ravi AU - Velu,Vijayakumar AU - Titanji,Kehmia AU - Bosinger,Steven E AU - Freeman,Gordon J AU - Silvestri,Guido AU - Amara,Rama Rao TI - PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques SN - 1558-8238 PY - 2012///0629 KW - Animals KW - Antibodies, Neutralizing KW - pharmacology KW - Antiviral Agents KW - Bacteremia KW - blood KW - Bacterial Translocation KW - Campylobacter KW - immunology KW - Chronic Disease KW - Feces KW - microbiology KW - Gene Expression Profiling KW - Humans KW - Interferon Type I KW - Intestinal Mucosa KW - drug effects KW - Intestine, Large KW - Lipopolysaccharides KW - Macaca mulatta KW - Opportunistic Infections KW - Programmed Cell Death 1 Receptor KW - antagonists & inhibitors KW - Salmonella KW - Shigella KW - Signal Transduction KW - Simian Acquired Immunodeficiency Syndrome KW - drug therapy KW - Simian Immunodeficiency Virus KW - Transcription, Genetic KW - Trichuris N1 - Publication Type: Journal Article UR - https://doi.org/10.1172/JCI60612 ER -