TY - GEN AU - Westra,Edze R AU - van Erp,Paul B G AU - Künne,Tim AU - Wong,Shi Pey AU - Staals,Raymond H J AU - Seegers,Christel L C AU - Bollen,Sander AU - Jore,Matthijs M AU - Semenova,Ekaterina AU - Severinov,Konstantin AU - de Vos,Willem M AU - Dame,Remus T AU - de Vries,Renko AU - Brouns,Stan J J AU - van der Oost,John TI - CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 SN - 1097-4164 PY - 2012///0830 KW - CRISPR-Associated Proteins KW - DNA Helicases KW - genetics KW - DNA, Superhelical KW - metabolism KW - Escherichia coli K12 KW - Escherichia coli Proteins KW - Models, Immunological KW - Nucleic Acid Conformation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.molcel.2012.03.018 ER -