Ghassabian, Sussan <br/><br/>
Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites.  [electronic resource] 

 -  Biochemical pharmacology  Jul 2012 
 - 215-23 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1873-2968 
<br/><br/><label>Standard No.: </label>10.1016/j.bcp.2012.04.001  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Benzenesulfonates--metabolism<br/>Catalytic Domain<br/>Cytochrome P-450 CYP3A--chemistry<br/>Humans<br/>Inactivation, Metabolic<br/>Microsomes, Liver--drug effects<br/>Models, Molecular<br/>Niacinamide--analogs & derivatives<br/>Oxidation-Reduction<br/>Phenylurea Compounds<br/>Protein Conformation<br/>Pyridines--metabolism<br/>Sorafenib