TY - GEN AU - Chang,Li-Ju AU - Eastman,Alan TI - Decreased translation of p21waf1 mRNA causes attenuated p53 signaling in some p53 wild-type tumors SN - 1551-4005 PY - 2012///0917 KW - Camptothecin KW - analogs & derivatives KW - Cell Cycle Checkpoints KW - Checkpoint Kinase 1 KW - Cyclin-Dependent Kinase Inhibitor p21 KW - genetics KW - DNA Damage KW - Gene Expression Regulation, Neoplastic KW - HCT116 Cells KW - Half-Life KW - Humans KW - Irinotecan KW - Kinetics KW - Phosphorylation KW - Polyribosomes KW - metabolism KW - Protein Biosynthesis KW - Protein Kinases KW - Pyrazoles KW - pharmacology KW - Pyrimidines KW - RNA, Messenger KW - RNA, Neoplasm KW - Signal Transduction KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.4161/cc.20208 ER -