TY - GEN AU - Thampi,Prajitha AU - Rao,Haripriya Vittal AU - Mitter,Sayak K AU - Cai,Jun AU - Mao,Haoyu AU - Li,Hong AU - Seo,Soojung AU - Qi,Xiaoping AU - Lewin,Alfred S AU - Romano,Carl AU - Boulton,Michael E TI - The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium SN - 1932-6203 PY - 2012///0820 KW - 8-Hydroxy-2-(di-n-propylamino)tetralin KW - pharmacology KW - Aged KW - Aged, 80 and over KW - Animals KW - Antioxidants KW - metabolism KW - Cell Line KW - Cytoprotection KW - drug effects KW - Humans KW - Lipofuscin KW - Macular Degeneration KW - Mice KW - Middle Aged KW - Mitochondria KW - Oxidative Stress KW - Receptors, Serotonin KW - Retinal Pigment Epithelium KW - cytology KW - Serotonin Receptor Agonists KW - Superoxides KW - Vision, Ocular N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0034468 ER -