TY - GEN AU - Sajish,Mathew AU - Zhou,Quansheng AU - Kishi,Shuji AU - Valdez,Delgado M AU - Kapoor,Mili AU - Guo,Min AU - Lee,Sunhee AU - Kim,Sunghoon AU - Yang,Xiang-Lei AU - Schimmel,Paul TI - Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling SN - 1552-4469 PY - 2012///0716 KW - Animals KW - Catalytic Domain KW - Cell Culture Techniques KW - Cell Nucleus KW - drug effects KW - Cytoplasm KW - DNA-Activated Protein Kinase KW - genetics KW - Electrophoresis, Polyacrylamide Gel KW - Embryo, Nonmammalian KW - enzymology KW - HeLa Cells KW - Humans KW - Immunoprecipitation KW - Interferon-gamma KW - pharmacology KW - Microscopy, Confocal KW - Models, Molecular KW - Phosphorylation KW - Poly (ADP-Ribose) Polymerase-1 KW - Poly(ADP-ribose) Polymerases KW - Protein Interaction Maps KW - Signal Transduction KW - Transfection KW - Tryptophan-tRNA Ligase KW - Tumor Suppressor Protein p53 KW - Zebrafish KW - embryology N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nchembio.937 ER -