TY  - GEN
AU  - Wroblewska,Aleksandra
AU  - van Haren,Simon D
AU  - Herczenik,Eszter
AU  - Kaijen,Paul
AU  - Ruminska,Aleksandra
AU  - Jin,Sheng-Yu
AU  - Zheng,X Long
AU  - van den Biggelaar,Maartje
AU  - ten Brinke,Anja
AU  - Meijer,Alexander B
AU  - Voorberg,Jan
TI  - Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice
SN  - 1528-0020
PY  - 2012///0730
KW  - Amino Acid Substitution
KW  - Animals
KW  - Antibodies, Neutralizing
KW  - immunology
KW  - Autoantibodies
KW  - Blood Coagulation Factor Inhibitors
KW  - CD4-Positive T-Lymphocytes
KW  - Dendritic Cells
KW  - Disease Models, Animal
KW  - Factor VIII
KW  - genetics
KW  - Hemophilia A
KW  - drug therapy
KW  - Humans
KW  - Macrophages
KW  - Mice
KW  - Mice, Knockout
KW  - Monocytes
KW  - Mutation, Missense
KW  - Protein Structure, Tertiary
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1182/blood-2011-11-391680
ER  -