TY - GEN AU - Cao,Qi AU - McIsaac,Shayla M AU - Stadnyk,Andrew W TI - Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway SN - 1522-1563 PY - 2012///0823 KW - Caco-2 Cells KW - Cell Polarity KW - Cell Proliferation KW - Colon KW - drug effects KW - Complement Activation KW - Complement C5a KW - genetics KW - Epithelial Cells KW - Extracellular Signal-Regulated MAP Kinases KW - antagonists & inhibitors KW - HT29 Cells KW - Humans KW - Immunity, Innate KW - Immunity, Mucosal KW - Inflammation KW - enzymology KW - Interleukin-8 KW - Intestinal Absorption KW - Intestinal Mucosa KW - MAP Kinase Signaling System KW - Permeability KW - Phenotype KW - Protein Kinase Inhibitors KW - pharmacology KW - RNA, Messenger KW - metabolism KW - Receptor, Anaphylatoxin C5a KW - Receptors, Chemokine KW - Receptors, Complement KW - Time Factors KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1152/ajpcell.00213.2011 ER -