Martínez de Lizarrondo, Sara
Synergistic effect of thrombin and CD40 ligand on endothelial matrix metalloproteinase-10 expression and microparticle generation in vitro and in vivo. [electronic resource]
- Arteriosclerosis, thrombosis, and vascular biology Jun 2012
- 1477-87 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 1524-4636
Standard No.: 10.1161/ATVBAHA.112.248773 doi
Subjects--Topical Terms: Adult Aged Aged, 80 and over Animals Antibodies--pharmacology Blood Coagulation CD40 Antigens--antagonists & inhibitors CD40 Ligand--antagonists & inhibitors Case-Control Studies Cell-Derived Microparticles--enzymology Cells, Cultured Disease Models, Animal Disseminated Intravascular Coagulation--enzymology Endothelial Cells--drug effects Endotoxemia--enzymology Female Gene Expression Regulation, Enzymologic Hirudins--pharmacology Human Umbilical Vein Endothelial Cells--enzymology Humans Lipopolysaccharides--pharmacology Male Matrix Metalloproteinase 10--blood Mice Mice, Inbred C57BL Mice, Knockout Middle Aged Mitogen-Activated Protein Kinase 8--antagonists & inhibitors Multivariate Analysis Peptides--pharmacology Protein Kinase Inhibitors--pharmacology RNA, Messenger--metabolism Receptor, PAR-1--agonists Risk Assessment Risk Factors Sepsis--enzymology Signal Transduction Spain Survival Analysis Thrombin--metabolism Time Factors Up-Regulation p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors Platelet Aggregation Inhibitors