Martínez de Lizarrondo, Sara

Synergistic effect of thrombin and CD40 ligand on endothelial matrix metalloproteinase-10 expression and microparticle generation in vitro and in vivo. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology Jun 2012 - 1477-87 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4636

10.1161/ATVBAHA.112.248773 doi


Adult
Aged
Aged, 80 and over
Animals
Antibodies--pharmacology
Blood Coagulation
CD40 Antigens--antagonists & inhibitors
CD40 Ligand--antagonists & inhibitors
Case-Control Studies
Cell-Derived Microparticles--enzymology
Cells, Cultured
Disease Models, Animal
Disseminated Intravascular Coagulation--enzymology
Endothelial Cells--drug effects
Endotoxemia--enzymology
Female
Gene Expression Regulation, Enzymologic
Hirudins--pharmacology
Human Umbilical Vein Endothelial Cells--enzymology
Humans
Lipopolysaccharides--pharmacology
Male
Matrix Metalloproteinase 10--blood
Mice
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Mitogen-Activated Protein Kinase 8--antagonists & inhibitors
Multivariate Analysis
Peptides--pharmacology
Protein Kinase Inhibitors--pharmacology
RNA, Messenger--metabolism
Receptor, PAR-1--agonists
Risk Assessment
Risk Factors
Sepsis--enzymology
Signal Transduction
Spain
Survival Analysis
Thrombin--metabolism
Time Factors
Up-Regulation
p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors
Platelet Aggregation Inhibitors