TY - GEN AU - Stefanova,Nadia AU - Kaufmann,Walter A AU - Humpel,Christian AU - Poewe,Werner AU - Wenning,Gregor K TI - Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy SN - 1432-0533 PY - 2012///1030 KW - 2',3'-Cyclic-Nucleotide Phosphodiesterases KW - metabolism KW - Analysis of Variance KW - Animals KW - Autophagy KW - drug effects KW - Brain KW - Dopamine and cAMP-Regulated Phosphoprotein 32 KW - Exploratory Behavior KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Microscopy, Immunoelectron KW - Motor Activity KW - Myelin Proteolipid Protein KW - genetics KW - Neurodegenerative Diseases KW - chemically induced KW - Oligodendroglia KW - Oligopeptides KW - toxicity KW - Proteasome Endopeptidase Complex KW - Time Factors KW - Tyrosine 3-Monooxygenase KW - Ubiquitin KW - alpha-Synuclein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s00401-012-0977-5 ER -