TY  - GEN
AU  - Yap,T A
AU  - Cortes-Funes,H
AU  - Shaw,H
AU  - Rodriguez,R
AU  - Olmos,D
AU  - Lal,R
AU  - Fong,P C
AU  - Tan,D S
AU  - Harris,D
AU  - Capdevila,J
AU  - Coronado,C
AU  - Alfaro,V
AU  - Soto-Matos,A
AU  - Fernández-Teruel,C
AU  - Siguero,M
AU  - Tabernero,J M
AU  - Paz-Ares,L
AU  - de Bono,J S
AU  - López-Martin,J A
TI  - First-in-man phase I trial of two schedules of the novel synthetic tetrahydroisoquinoline alkaloid PM00104 (Zalypsis) in patients with advanced solid tumours
SN  - 1532-1827
PY  - 2012///0625
KW  - Adult
KW  - Aged
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Disease Progression
KW  - Dose-Response Relationship, Drug
KW  - Drug Administration Schedule
KW  - Female
KW  - Humans
KW  - Male
KW  - Maximum Tolerated Dose
KW  - Middle Aged
KW  - Neoplasms
KW  - classification
KW  - Tetrahydroisoquinolines
KW  - Young Adult
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/bjc.2012.99
ER  -