Effects of combined endothelin A receptor and renin-angiotensin system blockade on the course of end-organ damage in 5/6 nephrectomized Ren-2 hypertensive rats. [electronic resource]
- Kidney & blood pressure research 2012
- 382-92 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1423-0143
10.1159/000336823 doi
Angiotensin II Type 1 Receptor Blockers--pharmacology Angiotensin-Converting Enzyme Inhibitors--pharmacology Animals Atrasentan Disease Models, Animal Drug Therapy, Combination Endothelin A Receptor Antagonists Hypertension, Renal--drug therapy Indoles--pharmacology Kidney--pathology Losartan--pharmacology Male Nephrectomy--methods Pyrrolidines--pharmacology Rats Rats, Sprague-Dawley Rats, Transgenic Receptor, Angiotensin, Type 1--metabolism Receptor, Endothelin A--metabolism Renal Insufficiency, Chronic--drug therapy Renin-Angiotensin System--drug effects Survival Analysis Treatment Outcome