A selective estrogen receptor modulator inhibits tumor necrosis factor-α-induced apoptosis through the ERK1/2 signaling pathway in human chondrocytes. [electronic resource]
- Biochemical and biophysical research communications May 2012
- 418-24 p. digital
Publication Type: Journal Article
1090-2104
10.1016/j.bbrc.2012.03.111 doi
Apoptosis--drug effects Cell Line, Tumor Cell Survival Chondrocytes--drug effects Enzyme Activation Humans MAP Kinase Kinase 4--biosynthesis MAP Kinase Signaling System Mitogen-Activated Protein Kinase 1--biosynthesis Mitogen-Activated Protein Kinase 3--biosynthesis Proto-Oncogene Proteins c-akt--biosynthesis RNA, Small Interfering--genetics Raloxifene Hydrochloride--pharmacology Selective Estrogen Receptor Modulators--pharmacology Tumor Necrosis Factor-alpha--antagonists & inhibitors p38 Mitogen-Activated Protein Kinases--biosynthesis