Duong, MyLinh T

LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients. [electronic resource] - PLoS genetics 2012 - e1002538 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1553-7404

10.1371/journal.pgen.1002538 doi


Acinar Cells--cytology
Animals
Benzenesulfonates--pharmacology
Breast Neoplasms--genetics
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Transformation, Neoplastic--drug effects
Cyclin E--genetics
Cyclin-Dependent Kinase 2--antagonists & inhibitors
Female
Gene Expression Regulation, Neoplastic
Humans
Kaplan-Meier Estimate
MAP Kinase Signaling System--genetics
Mammary Glands, Animal--metabolism
Mice
Mice, Nude
Neoplasm Invasiveness--genetics
Niacinamide--analogs & derivatives
Phenylurea Compounds
Prognosis
Protein Isoforms--genetics
Proto-Oncogene Proteins B-raf--antagonists & inhibitors
Purines--pharmacology
Pyridines--pharmacology
Retrospective Studies
Roscovitine
Sirolimus--pharmacology
Sorafenib
TOR Serine-Threonine Kinases--antagonists & inhibitors