TY - GEN AU - Dewdney,Alice AU - Cunningham,David AU - Tabernero,Josep AU - Capdevila,Jaume AU - Glimelius,Bengt AU - Cervantes,Andres AU - Tait,Diana AU - Brown,Gina AU - Wotherspoon,Andrew AU - Gonzalez de Castro,David AU - Chua,Yu Jo AU - Wong,Rachel AU - Barbachano,Yolanda AU - Oates,Jacqueline AU - Chau,Ian TI - Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C) SN - 1527-7755 PY - 2012///0712 KW - Adenocarcinoma KW - mortality KW - Adult KW - Aged KW - Analysis of Variance KW - Antibodies, Monoclonal KW - administration & dosage KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Combined Chemotherapy Protocols KW - Capecitabine KW - Cetuximab KW - Chemoradiotherapy, Adjuvant KW - methods KW - Colectomy KW - Combined Modality Therapy KW - Deoxycytidine KW - Disease-Free Survival KW - Female KW - Fluorouracil KW - Follow-Up Studies KW - Humans KW - Intestinal Mucosa KW - surgery KW - Kaplan-Meier Estimate KW - Logistic Models KW - Male KW - Middle Aged KW - Neoadjuvant Therapy KW - Neoplasm Invasiveness KW - pathology KW - Neoplasm Staging KW - Organoplatinum Compounds KW - Oxaliplatin KW - Preoperative Care KW - Radiotherapy, Adjuvant KW - Rectal Neoplasms KW - Risk Assessment KW - Survival Analysis KW - Treatment Outcome KW - United Kingdom N1 - Publication Type: Clinical Trial, Phase II; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1200/JCO.2011.39.6036 ER -