TY - GEN AU - Ji,Wen-Tsai AU - Yang,Sheng-Ru AU - Chen,Jeff Yi-Fu AU - Cheng,Ya-Ping AU - Lee,Ying-Ray AU - Chiang,Ming-Ko AU - Chen,Hau-Ren TI - Arecoline downregulates levels of p21 and p27 through the reactive oxygen species/mTOR complex 1 pathway and may contribute to oral squamous cell carcinoma SN - 1349-7006 PY - 2013///0408 KW - Arecoline KW - pharmacology KW - Blotting, Western KW - Carcinoma, Squamous Cell KW - genetics KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Cholinergic Agonists KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclin-Dependent Kinase Inhibitor p27 KW - DNA Damage KW - Down-Regulation KW - G1 Phase Cell Cycle Checkpoints KW - G2 Phase Cell Cycle Checkpoints KW - Humans KW - Male KW - Mechanistic Target of Rapamycin Complex 1 KW - Microscopy, Fluorescence KW - Mouth Neoplasms KW - Multiprotein Complexes KW - Reactive Oxygen Species KW - metabolism KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - TOR Serine-Threonine Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1349-7006.2012.02294.x ER -