TY - GEN AU - Halestrap,A P AU - Davidson,A M TI - Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase SN - 0264-6021 PY - 1990///0628 KW - Adenosine Diphosphate KW - pharmacology KW - Amino Acid Isomerases KW - antagonists & inhibitors KW - Animals KW - Bongkrekic Acid KW - Calcium KW - Cell Membrane Permeability KW - Cyclosporins KW - metabolism KW - Kinetics KW - Light KW - Mitochondria, Heart KW - drug effects KW - Mitochondria, Liver KW - Mitochondrial ADP, ATP Translocases KW - Mitochondrial Swelling KW - Nucleotidyltransferases KW - Peptidylprolyl Isomerase KW - Rats KW - Scattering, Radiation KW - Sucrose KW - Thiocyanates N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1042/bj2680153 ER -