Gallardo, A <br/><br/>
Increased signalling of EGFR and IGF1R, and deregulation of PTEN/PI3K/Akt pathway are related with trastuzumab resistance in HER2 breast carcinomas.  [electronic resource] 

 -  British journal of cancer  Apr 2012 
 - 1367-73 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1532-1827 
<br/><br/><label>Standard No.: </label>10.1038/bjc.2012.85  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Antibodies, Monoclonal, Humanized--pharmacology<br/>Breast Neoplasms--diagnosis<br/>Drug Resistance, Neoplasm--drug effects<br/>ErbB Receptors--metabolism<br/>Female<br/>Humans<br/>Middle Aged<br/>Neoplasm Staging<br/>PTEN Phosphohydrolase--metabolism<br/>Phosphatidylinositol 3-Kinases--genetics<br/>Prognosis<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Receptor, ErbB-2--genetics<br/>Receptor, IGF Type 1--metabolism<br/>Signal Transduction--drug effects<br/>Survival Analysis<br/>Trastuzumab