Detection of allosteric kinase inhibitors by displacement of active site probes. [electronic resource]
- Journal of biomolecular screening Jul 2012
- 813-21 p. digital
Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
1552-454X
10.1177/1087057112439889 doi
Adenosine Triphosphate--metabolism Allosteric Regulation--drug effects Binding, Competitive Catalytic Domain--drug effects Drug Evaluation, Preclinical--methods Fluorescence Resonance Energy Transfer Fusion Proteins, bcr-abl--antagonists & inhibitors Humans Inhibitory Concentration 50 MAP Kinase Kinase 1--antagonists & inhibitors Protein Binding Protein Kinase Inhibitors--chemistry Protein-Tyrosine Kinases--antagonists & inhibitors