Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy. [electronic resource]
- Blood May 2012
- 4686-97 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1528-0020
10.1182/blood-2011-09-377846 doi
Biological Availability Cell Line, Tumor Cell Proliferation Cell Survival--genetics Cells, Cultured Disease Progression Drug Evaluation, Preclinical Gene Expression Regulation, Neoplastic--drug effects Glucose--metabolism Glucose Transport Proteins, Facilitative--antagonists & inhibitors Glucose Transporter Type 4--antagonists & inhibitors HIV Protease Inhibitors--pharmacology Humans Molecular Targeted Therapy--methods Multiple Myeloma--genetics Off-Label Use Primary Cell Culture Ritonavir--pharmacology