TY  - GEN
AU  - Gill,Sumandeep K
AU  - Xu,Hao
AU  - Kirchhoff,Paul D
AU  - Cierpicki,Tomasz
AU  - Turbiak,Anjanette J
AU  - Wan,Baojie
AU  - Zhang,Nan
AU  - Peng,Kuan-Wei
AU  - Franzblau,Scott G
AU  - Garcia,George A
AU  - Showalter,H D Hollis
TI  - Structure-based design of novel benzoxazinorifamycins with potent binding affinity to wild-type and rifampin-resistant mutant Mycobacterium tuberculosis RNA polymerases
SN  - 1520-4804
PY  - 2012///0717
KW  - Animals
KW  - Antibiotics, Antitubercular
KW  - chemical synthesis
KW  - Benzoxazines
KW  - DNA-Directed RNA Polymerases
KW  - metabolism
KW  - Drug Design
KW  - Drug Resistance, Bacterial
KW  - Mice
KW  - Mycobacterium tuberculosis
KW  - drug effects
KW  - Rifampin
KW  - pharmacology
KW  - Rifamycins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm201716n
ER  -