TY  - GEN
AU  - Chen,Zhao
AU  - Cheng,Katherine
AU  - Walton,Zandra
AU  - Wang,Yuchuan
AU  - Ebi,Hiromichi
AU  - Shimamura,Takeshi
AU  - Liu,Yan
AU  - Tupper,Tanya
AU  - Ouyang,Jing
AU  - Li,Jie
AU  - Gao,Peng
AU  - Woo,Michele S
AU  - Xu,Chunxiao
AU  - Yanagita,Masahiko
AU  - Altabef,Abigail
AU  - Wang,Shumei
AU  - Lee,Charles
AU  - Nakada,Yuji
AU  - Peña,Christopher G
AU  - Sun,Yanping
AU  - Franchetti,Yoko
AU  - Yao,Catherine
AU  - Saur,Amy
AU  - Cameron,Michael D
AU  - Nishino,Mizuki
AU  - Hayes,D Neil
AU  - Wilkerson,Matthew D
AU  - Roberts,Patrick J
AU  - Lee,Carrie B
AU  - Bardeesy,Nabeel
AU  - Butaney,Mohit
AU  - Chirieac,Lucian R
AU  - Costa,Daniel B
AU  - Jackman,David
AU  - Sharpless,Norman E
AU  - Castrillon,Diego H
AU  - Demetri,George D
AU  - Jänne,Pasi A
AU  - Pandolfi,Pier Paolo
AU  - Cantley,Lewis C
AU  - Kung,Andrew L
AU  - Engelman,Jeffrey A
AU  - Wong,Kwok-Kin
TI  - A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response
SN  - 1476-4687
PY  - 2012///0508
KW  - AMP-Activated Protein Kinases
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - Benzimidazoles
KW  - pharmacology
KW  - Biomarkers, Tumor
KW  - genetics
KW  - Clinical Trials, Phase II as Topic
KW  - Disease Models, Animal
KW  - Docetaxel
KW  - Drug Evaluation, Preclinical
KW  - Fluorodeoxyglucose F18
KW  - Genes, p53
KW  - Humans
KW  - Lung Neoplasms
KW  - drug therapy
KW  - MAP Kinase Signaling System
KW  - drug effects
KW  - Mice
KW  - Mitogen-Activated Protein Kinase Kinases
KW  - antagonists & inhibitors
KW  - Mutation
KW  - Pharmacogenetics
KW  - methods
KW  - Positron-Emission Tomography
KW  - Protein Serine-Threonine Kinases
KW  - deficiency
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Randomized Controlled Trials as Topic
KW  - Reproducibility of Results
KW  - Taxoids
KW  - therapeutic use
KW  - Tomography, X-Ray Computed
KW  - Treatment Outcome
KW  - ras Proteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nature10937
ER  -