TY  - GEN
AU  - Yang,Fan
AU  - Jove,Veronica
AU  - Buettner,Ralf
AU  - Xin,Hong
AU  - Wu,Jun
AU  - Wang,Yan
AU  - Nam,Sangkil
AU  - Xu,Yibing
AU  - Ara,Tasnim
AU  - DeClerck,Yves A
AU  - Seeger,Robert
AU  - Yu,Hua
AU  - Jove,Richard
TI  - Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis
SN  - 1555-8576
PY  - 2012///1214
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Apoptosis
KW  - drug effects
KW  - Apoptosis Regulatory Proteins
KW  - genetics
KW  - Benzenesulfonates
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Interleukin-6
KW  - metabolism
KW  - Janus Kinase 2
KW  - Lysophospholipids
KW  - Mice
KW  - Mice, Inbred NOD
KW  - Mice, SCID
KW  - Mitogen-Activated Protein Kinases
KW  - Neuroblastoma
KW  - drug therapy
KW  - Niacinamide
KW  - analogs & derivatives
KW  - Phenylurea Compounds
KW  - Phosphorylation
KW  - Pyridines
KW  - STAT3 Transcription Factor
KW  - Signal Transduction
KW  - Sorafenib
KW  - Sphingosine
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.4161/cbt.19603
ER  -