Yang, Fan <br/><br/>
Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis.  [electronic resource] 

 -  Cancer biology & therapy  May 2012 
 - 534-41 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1555-8576 
<br/><br/><label>Standard No.: </label>10.4161/cbt.19603  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--administration & dosage<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--genetics<br/>Benzenesulfonates--administration & dosage<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Female<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Interleukin-6--metabolism<br/>Janus Kinase 2--metabolism<br/>Lysophospholipids--metabolism<br/>Mice<br/>Mice, Inbred NOD<br/>Mice, SCID<br/>Mitogen-Activated Protein Kinases--metabolism<br/>Neuroblastoma--drug therapy<br/>Niacinamide--analogs & derivatives<br/>Phenylurea Compounds<br/>Phosphorylation--drug effects<br/>Pyridines--administration & dosage<br/>STAT3 Transcription Factor--metabolism<br/>Signal Transduction--drug effects<br/>Sorafenib<br/>Sphingosine--analogs & derivatives<br/>Xenograft Model Antitumor Assays