Chang, Yu-Chung E <br/><br/>
Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.  [electronic resource] 

 -  Journal of medicinal chemistry  Apr 2012 
 - 3387-97 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm300072d  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Carbamates--chemistry<br/>Catalytic Domain<br/>Crystallography, X-Ray<br/>Drug Resistance, Viral<br/>HIV Protease--chemistry<br/>HIV Protease Inhibitors--chemistry<br/>HIV-1--enzymology<br/>Kinetics<br/>Models, Molecular<br/>Molecular Conformation<br/>Mutation<br/>Pyrrolidinones--chemistry<br/>Sulfonamides--chemistry