TY  - GEN
AU  - Helldén,A
AU  - Panagiotidis,G
AU  - Johansson,P
AU  - Waters,N
AU  - Waters,S
AU  - Tedroff,J
AU  - Bertilsson,L
TI  - The dopaminergic stabilizer pridopidine is to a major extent N-depropylated by CYP2D6 in humans
SN  - 1432-1041
PY  - 2012///1226
KW  - Administration, Oral
KW  - Adult
KW  - Area Under Curve
KW  - Biotransformation
KW  - Cytochrome P-450 CYP2D6
KW  - metabolism
KW  - Cytochrome P-450 CYP2D6 Inhibitors
KW  - Dealkylation
KW  - Dopamine Antagonists
KW  - administration & dosage
KW  - Enzyme Inhibitors
KW  - pharmacokinetics
KW  - Glomerular Filtration Rate
KW  - Half-Life
KW  - Humans
KW  - Intestinal Absorption
KW  - Kidney
KW  - Metabolic Clearance Rate
KW  - Middle Aged
KW  - Phenotype
KW  - Piperidines
KW  - Sweden
KW  - White People
KW  - Young Adult
N1  - Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00228-012-1248-z
ER  -