Helldén, A <br/><br/>
The dopaminergic stabilizer pridopidine is to a major extent N-depropylated by CYP2D6 in humans.  [electronic resource] 

 -  European journal of clinical pharmacology  Sep 2012 
 - 1281-6 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1432-1041 
<br/><br/><label>Standard No.: </label>10.1007/s00228-012-1248-z  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Administration, Oral<br/>Adult<br/>Area Under Curve<br/>Biotransformation<br/>Cytochrome P-450 CYP2D6--metabolism<br/>Cytochrome P-450 CYP2D6 Inhibitors<br/>Dealkylation<br/>Dopamine Antagonists--administration & dosage<br/>Enzyme Inhibitors--pharmacokinetics<br/>Glomerular Filtration Rate<br/>Half-Life<br/>Humans<br/>Intestinal Absorption<br/>Kidney--metabolism<br/>Metabolic Clearance Rate<br/>Middle Aged<br/>Phenotype<br/>Piperidines--administration & dosage<br/>Sweden<br/>White People<br/>Young Adult