Krenzlin, Harald <br/><br/>
DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress.  [electronic resource] 

 -  PLoS genetics  2012 
 - e1002557 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1553-7404 
<br/><br/><label>Standard No.: </label>10.1371/journal.pgen.1002557  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Bleomycin--pharmacology<br/>Cell Cycle Proteins--genetics<br/>Cells, Cultured<br/>DNA Breaks, Double-Stranded<br/>DNA Damage--drug effects<br/>DNA-Binding Proteins<br/>Gene Expression Regulation<br/>Gene Knockdown Techniques<br/>Humans<br/>Mice<br/>Mice, Mutant Strains<br/>NAD--metabolism<br/>Nijmegen Breakage Syndrome--genetics<br/>Nuclear Proteins--genetics<br/>Oxidative Stress--drug effects<br/>Poly (ADP-Ribose) Polymerase-1<br/>Poly(ADP-ribose) Polymerase Inhibitors<br/>Poly(ADP-ribose) Polymerases--genetics<br/>Reactive Oxygen Species--metabolism<br/>Transcriptional Activation