TY - GEN AU - Li,X AU - Stevens,P D AU - Yang,H AU - Gulhati,P AU - Wang,W AU - Evers,B M AU - Gao,T TI - The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer SN - 1476-5594 PY - 2013///0604 KW - Animals KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Transformation, Neoplastic KW - genetics KW - Colonic Neoplasms KW - enzymology KW - Endopeptidases KW - Genes, Tumor Suppressor KW - HCT116 Cells KW - HEK293 Cells KW - Humans KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Nuclear Proteins KW - Phosphoprotein Phosphatases KW - Protein Binding KW - Protein Interaction Domains and Motifs KW - Protein Isoforms KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - Ubiquitination KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/onc.2012.66 ER -