Li, X

The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer. [electronic resource] - Oncogene Jan 2013 - 471-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-5594

10.1038/onc.2012.66 doi


Animals
Cell Line, Tumor
Cell Proliferation
Cell Transformation, Neoplastic--genetics
Colonic Neoplasms--enzymology
Endopeptidases--genetics
Genes, Tumor Suppressor
HCT116 Cells
HEK293 Cells
Humans
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Nuclear Proteins--genetics
Phosphoprotein Phosphatases--genetics
Protein Binding
Protein Interaction Domains and Motifs
Protein Isoforms
Proto-Oncogene Proteins c-akt--genetics
Signal Transduction
Ubiquitination
Up-Regulation