TY - GEN AU - Gong,Inna Y AU - Crown,Natalie AU - Suen,Colin M AU - Schwarz,Ute I AU - Dresser,George K AU - Knauer,Michael J AU - Sugiyama,Daisuke AU - DeGorter,Marianne K AU - Woolsey,Sarah AU - Tirona,Rommel G AU - Kim,Richard B TI - Clarifying the importance of CYP2C19 and PON1 in the mechanism of clopidogrel bioactivation and in vivo antiplatelet response SN - 1522-9645 PY - 2013///0429 KW - Adolescent KW - Adult KW - Area Under Curve KW - Aryl Hydrocarbon Hydroxylases KW - genetics KW - Aryldialkylphosphatase KW - Biotransformation KW - drug effects KW - Clopidogrel KW - Cytochrome P-450 CYP2C19 KW - Cytochrome P-450 CYP3A KW - Enzyme Inhibitors KW - pharmacokinetics KW - Humans KW - Midazolam KW - Middle Aged KW - Platelet Aggregation KW - Platelet Aggregation Inhibitors KW - Polymorphism, Genetic KW - Ticlopidine KW - analogs & derivatives KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/eurheartj/ehs042 ER -