TY - GEN AU - Haldar,Shubhasis AU - Paul,Simantasarani AU - Joshi,Nidhi AU - Dasgupta,Anindya AU - Chattopadhyay,Krishnananda TI - The presence of the iron-sulfur motif is important for the conformational stability of the antiviral protein, Viperin SN - 1932-6203 PY - 2012///0629 KW - Amino Acid Motifs KW - Antiviral Agents KW - chemistry KW - Circular Dichroism KW - Computational Biology KW - Cysteine KW - metabolism KW - Electrophoresis, Polyacrylamide Gel KW - Humans KW - Hydrophobic and Hydrophilic Interactions KW - drug effects KW - Iron-Sulfur Proteins KW - Male KW - Models, Molecular KW - Mutant Proteins KW - Oxidoreductases Acting on CH-CH Group Donors KW - Protein Folding KW - Protein Stability KW - Protein Structure, Tertiary KW - Proteins KW - Spectrometry, Fluorescence KW - Spectrophotometry, Ultraviolet KW - Structure-Activity Relationship KW - Thermodynamics KW - Trifluoroethanol KW - pharmacology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0031797 ER -