Cook, Natalie <br/><br/>
Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma.  [electronic resource] 

 -  The Journal of experimental medicine  Mar 2012 
 - 437-44 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1540-9538 
<br/><br/><label>Standard No.: </label>10.1084/jem.20111923  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amyloid Precursor Protein Secretases--antagonists & inhibitors<br/>Animals<br/>Carcinoma, Pancreatic Ductal--blood supply<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cyclic S-Oxides--administration & dosage<br/>Deoxycytidine--administration & dosage<br/>Drug Synergism<br/>Drug Therapy, Combination<br/>Endothelial Cells--drug effects<br/>Humans<br/>Hypoxia--chemically induced<br/>Mice<br/>Mice, Mutant Strains<br/>Necrosis<br/>Pancreatic Neoplasms--blood supply<br/>Protease Inhibitors--administration & dosage<br/>Receptors, Notch--metabolism<br/>Signal Transduction--drug effects<br/>Thiadiazoles--administration & dosage<br/>Translational Research, Biomedical<br/>Gemcitabine