TY - GEN AU - Ptasinska,A AU - Assi,S A AU - Mannari,D AU - James,S R AU - Williamson,D AU - Dunne,J AU - Hoogenkamp,M AU - Wu,M AU - Care,M AU - McNeill,H AU - Cauchy,P AU - Cullen,M AU - Tooze,R M AU - Tenen,D G AU - Young,B D AU - Cockerill,P N AU - Westhead,D R AU - Heidenreich,O AU - Bonifer,C TI - Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding SN - 1476-5551 PY - 2012///1119 KW - Acetylation KW - Binding Sites KW - CCAAT-Binding Factor KW - genetics KW - Cell Differentiation KW - Cell Line, Tumor KW - Chromatin KW - Chromosomes, Human, Pair 21 KW - Chromosomes, Human, Pair 8 KW - Cluster Analysis KW - Core Binding Factor Alpha 2 Subunit KW - Gene Expression Profiling KW - Gene Silencing KW - Histones KW - metabolism KW - Humans KW - Leukemia, Myeloid, Acute KW - Mutation KW - Oncogene Proteins, Fusion KW - Protein Binding KW - Proto-Oncogene Proteins KW - RNA Polymerase II KW - RUNX1 Translocation Partner 1 Protein KW - Transcription Factors KW - Transcriptional Activation KW - Translocation, Genetic N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/leu.2012.49 ER -