TY - GEN AU - Curik,N AU - Burda,P AU - Vargova,K AU - Pospisil,V AU - Belickova,M AU - Vlckova,P AU - Savvulidi,F AU - Necas,E AU - Hajkova,H AU - Haskovec,C AU - Cermak,J AU - Krivjanska,M AU - Trneny,M AU - Laslo,P AU - Jonasova,A AU - Stopka,T TI - 5-azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU.1 gene and cell differentiation capacity SN - 1476-5551 PY - 2012///1119 KW - Aged KW - Aged, 80 and over KW - Antimetabolites, Antineoplastic KW - pharmacology KW - Azacitidine KW - Cell Differentiation KW - drug effects KW - Cell Line, Tumor KW - Chromatin KW - genetics KW - Colony-Stimulating Factors KW - DNA Methylation KW - Female KW - Gene Expression Regulation, Leukemic KW - Humans KW - Male KW - Middle Aged KW - Myelodysplastic Syndromes KW - drug therapy KW - Neoplastic Stem Cells KW - cytology KW - Proto-Oncogene Proteins KW - Regulatory Sequences, Nucleic Acid KW - Trans-Activators KW - Transcriptional Activation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/leu.2012.47 ER -